Pearson Edexcel · GCSE · Biology

    Course version: 1BI0 · Version from Sept 2016

    Describe how the sex of offspring is determined at fertilisation, using…

    Full specification wording

    Topic 3 – Genetics: 3.15 Describe how the sex of offspring is determined at fertilisation, using genetic diagrams

    Human sex is determined at fertilisation by which sex chromosomes the sperm brings.

    Checked against the Pearson Edexcel 1BI0 specification (opens in a new tab) on .

    • Point 13 of 20

    Study notes

    From the checked teaching notes for this specification point.

    The idea

    Human sex is determined at fertilisation by which sex chromosomes the sperm brings. A female has two X chromosomes, so every egg carries one X. A male has one X and one Y, so half his sperm carry X and half carry Y. If an X-bearing sperm fertilises the egg the zygote is XX and develops as female; if a Y-bearing sperm fertilises it the zygote is XY and develops as male. Because the sperm type is a 50:50 chance, each fertilisation gives roughly equal numbers of each sex. A genetic diagram shows this: write the parents' sex chromosomes, put the egg's X across the top and the sperm's X and Y down the side, then combine them in the four boxes to give XX, XY, XX, XY. The diagram, not the environment, shows the outcome.

    What earns the marks

    • A female is XX, so all eggs contain a single X chromosome.
    • A male is XY, so sperm are of two types: half carry X and half carry Y.
    • At fertilisation the sperm's chromosome combines with the egg's X: X + X gives XX (female) and X + Y gives XY (male).
    • A genetic diagram (Punnett square) with egg X and sperm X/Y produces XX, XY, XX, XY, showing a 1:1 ratio of female to male.
    • The sex of the offspring is decided by the sperm, not the egg, because the egg always contributes X.

    Common mistakes and how to put them right

    • Thinking the mother determines the sex.

      Put it right by noting all eggs carry X, so only the sperm's X or Y changes the outcome.

    • Writing that a male is YY or a female is XY.

      Put it right: Correct to male XY and female XX.

    • Claiming the diagram guarantees exactly two boys and two girls.

      Put it right: Correct to a probability of about half each, not a fixed count.

    Exam tips

    • Always label the egg row and sperm column with the actual sex chromosomes before combining them.
    • State clearly that the sperm determines sex and explain why in one sentence.
    • When asked for a ratio, read it from the diagram boxes (for example 1:1) rather than guessing.

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    In humans, which chromosome combination in a fertilised egg produces a female offspring?

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